The distance between Rome and Brussels is 1.166 km or 729 miles.

Alitalia
Hubsdestinationsfleet

Alitalia has 3 daily flights from Rome (FCO) to Brussels (BRU) in the Summer of 2009.

AZ 156 with Airbus A321

AZ 160 with Air One Airbus A320

AZ 164 with Airbus A321

Flighttime 2 hours 15 minutes

Alitalia also flies from Milan to Brussels.

Brussels airlines
Hubsdestinationsfleet

Brussels airlines also flies between Rome (FCO) and Brussels airport (BRU) in the Summer of 2009. They do so up to 4 times a day with a mix of Boeing 737-400, Boeing 737-300 and Avro Jets.

From Rome to Brussels with Ryanair

This low cost carrier also links Rome to Brussels, but from secondary airports.